2020 May;31(3):e35. Read our, ClinicalTrials.gov Identifier: NCT01101451, Interventional STEP 1 REGISTRATION (RANDOMIZATION): Patients must not have an active infection requiring systemic therapy. Patients with melanoma of mucosal or acral origin are eligible. GLENDALE Medical Oncology Thunderbird Paseo Medical Plaza 5601 W Eugie Ave.,Ste 106 Glendale, AZ 85304 (QOPI) Certification Program, an affiliate of the American Society of Clinical Oncology - Learn More. STEP 1 REGISTRATION (RANDOMIZATION): Women of childbearing potential must have a negative urine or serum pregnancy test within 28 days prior to randomization. Palo Verde Cancer Specialists 7 reviews Claimed Medical Centers, Oncologist Edit All Rights Reserved. I. 8 Coping Tips for Chronic Migraine Sufferers, 11 Ways Migraines Are Dangerous for Your Health, 10 Things to Know About Psoriatic Arthritis, Your privacy is important to us. This content is not available in your current region. For general information, Learn About Clinical Studies. III. STEP 1 REGISTRATION (RANDOMIZATION): All patients must have disease status documented by a complete physical examination and imaging studies within 42 days prior to randomization. Human beings cannot live without hope, and shouldn't have to. I had had a PET scan showing possible, though explainable, points of metastatic cancer, which was followed by a clear PET scan. We will use exponential-mixture cure models to describe EFS patterns in the arms. Specialties: Palo Verde Cancer Specialist's team of physicians are trained and board certified in hematology and oncology and we work with other specialists to develop a personalized action plan that will improve your quality of life and better your chance of overcoming cancer. STEP 2 REGISTRATION (SURGERY): Patients must have disease assessments by CT chest/abdomen/pelvis with IV contrast, and neck CT with IV contrast if primary head and neck melanoma, performed within 42 days (and no more than 49 days) before the planned date of surgery. Palo Verde Cancer Specialists is dedicated to providing the most advanced and compassionate cancer care available in the Valley. Location Address Palo Verde Cancer Center Scottsdale offers Medical Oncology and Radiation Oncology services on site, by our highly skilled team of board certified physicians, technicians and nurses. Follow us on Facebook & Twitter. I. Giving pembrolizumab before and after surgery may work better compared to after surgery alone in treating melanoma. This randomized phase II trial studies how well fluorouracil, irinotecan hydrochloride, and oxaliplatin (combination chemotherapy) works and compares to gemcitabine hydrochloride and paclitaxel albumin-stabilized nanoparticle formulation before surgery in treating patients with pancreatic cancer that can be removed by surgery. STEP 1 REGISTRATION (RANDOMIZATION): All patients must have a CT or magnetic resonance imaging (MRI) of the brain within 42 days prior to randomization. Studies a U.S. FDA-regulated Drug Product: Studies a U.S. FDA-regulated Device Product: Computerized axial tomography (procedure), Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, Event-free survival (EFS) in patients with high-risk resectable melanoma randomized to neoadjuvant pembrolizumab with patients randomized to adjuvant pembrolizumab [TimeFrame:Date of randomization to date of first progression or death, assessed up to 10 years], Overall survival [TimeFrame:From date of randomization to date of death due to any cause, assessed up to 10 years], Disease control [TimeFrame:At 24 weeks], Local/regional control in the surgical site(s) [TimeFrame:Up to 10 years], Total number of pembrolizumab doses [TimeFrame:Up to 10 years], Pathologic response rate [TimeFrame:Up to 10 years], Response Evaluation Criteria in Solid Tumors (RECIST) 1.1 response rate [TimeFrame:Up to 10 years], Immune-related RECIST response rate [TimeFrame:Up to 10 years]. STEP 1 REGISTRATION (RANDOMIZATION): Absolute neutrophil count (ANC) >= 1,500/microliter (mcL) (within 42 days prior to randomization). (480) 941-1211 Telehealth services available Palo Verde Cancer Specialists is a medical group practice located in Scottsdale, AZ that specializes in Hematology & Oncology. ARM I: Patients undergo pelvic external-beam radiation therapy (EBRT) or intensity-modulated radiation therapy (IMRT) 5 days a week for 5.5 weeks. 9250 W Thomas Rd Ste 150, Phoenix AZ, 85037. Graded according to the active version of Common Terminology Criteria for Adverse Events (CTCAE). Your privacy is important to us. She even tracked me down midday, while I was driving to Tucson, to discuss my concerns. Patients also undergo collection of blood throughout the study and MRI or CT on study. Drugs used in chemotherapy, such as cisplatin, work in different ways to stop the growth of tumor cells, either by killing the cells, by stopping them from dividing, or by stopping them from spreading. Imaging studies must include a CT of the chest, abdomen and pelvis with intravenous contrast (unless contraindicated). STEP 1 REGISTRATION (RANDOMIZATION): Prior malignancy is allowed providing it does not require concurrent therapy. PVCS was the first practice to be certified by QOPI in Arizona. Unlike many other cancer treatment centers, our centers include a comprehensive array of life-saving treatments administered by board-certified hematologists, oncologists, and radiation oncologists. Palo Verde Cancer Specialists 5601 W Eugie Ave Ste 106 Glendale, AZ 85304 Tel: (602) 978-6255 Visit Website Accepting New Patients: Yes Medicare Accepted: Yes Gross or microscopic extracapsular nodal extension is permitted. Nodal, satellite/in-transit metastasis, distant metastases or disease in a prior complete lymphadenectomy basin must have been confirmed histologically by hematoxylin (H) & eosin (E) stained slides. STEP 1 REGISTRATION (RANDOMIZATION): Patients must not have received previous neoadjuvant treatment for their melanoma. View this study on Beta.ClinicalTrials.gov. Note: No testing for hepatitis B and hepatitis C is required unless mandated by local health authority. Patients must not be planning to receive any of the prohibited therapies during treatment phases on the study. Always consult a medical provider for diagnosis and treatment. Treatment repeats every 3 weeks for 18 cycles in the absence of disease progression or unacceptable toxicity. The content on Healthgrades does not provide medical advice. Is Palo Verde Cancer Specialists physically located within a hospital? Disease-free status must be documented by a complete physical examination and radiographic imaging studies within 42 days prior to Step 3 registration. (Clinical Trial), Randomized Phase III Clinical Trial of Adjuvant Radiation Versus Chemoradiation in Intermediate Risk, Stage I/IIA Cervical Cancer Treated With Initial Radical Hysterectomy and Pelvic Lymphadenectomy (NCT #01101451), Experimental: Arm II (cisplatin, EBRT, IMRT), 18 Years and older (Adult, Older Adult), Anchorage Associates in Radiation Medicine, Saint Joseph's Hospital and Medical Center, Fort Smith, Arkansas, United States, 72903, CHI Saint Vincent Cancer Center Hot Springs, Hot Springs, Arkansas, United States, 71913, Arroyo Grande, California, United States, 93420, Sutter Cancer Centers Radiation Oncology Services-Auburn, Alta Bates Summit Medical Center-Herrick Campus, Berkeley, California, United States, 94704, Providence Saint Joseph Medical Center/Disney Family Cancer Center, Burbank, California, United States, 91505, Burlingame, California, United States, 94010, Sutter Cancer Centers Radiation Oncology Services-Cameron Park, Cameron Park, California, United States, 95682, Carmichael, California, United States, 95608, Castro Valley, California, United States, 94546, Concord, California, United States, 94520, Elk Grove, California, United States, 95758, Loma Linda, California, United States, 92354, Los Angeles, California, United States, 90033, Los Angeles, California, United States, 90048, Modesto, California, United States, 95355, Palo Alto Medical Foundation-Camino Division, Mountain View, California, United States, 94040, Palo Alto Medical Foundation-Gynecologic Oncology, UC Irvine Health/Chao Family Comprehensive Cancer Center, Palo Alto, California, United States, 94301, Rocklin, California, United States, 95765, Sutter Cancer Centers Radiation Oncology Services-Roseville, Roseville, California, United States, 95661, Sacramento, California, United States, 95816, California Pacific Medical Center-Pacific Campus, San Francisco, California, United States, 94115, Pacific Central Coast Health Center-San Luis Obispo, San Luis Obispo, California, United States, 93401, Santa Cruz, California, United States, 95065, Mission Hope Medical Oncology - Santa Maria, Santa Maria, California, United States, 93444, Santa Rosa, California, United States, 95403, Sunnyvale, California, United States, 94086, Olive View-University of California Los Angeles Medical Center, Sutter Cancer Centers Radiation Oncology Services-Vacaville, Vacaville, California, United States, 95687, Sutter Solano Medical Center/Cancer Center, Vallejo, California, United States, 94589, Walnut Creek, California, United States, 94598, Woodland, California, United States, 95695, Colorado Springs, Colorado, United States, 80907, Presbyterian - Saint Lukes Medical Center - Health One, Mountain Blue Cancer Care Center - Swedish, Englewood, Colorado, United States, 80113, Saint Mary's Hospital and Regional Medical Center, Grand Junction, Colorado, United States, 81501, Rocky Mountain Cancer Centers-Greenwood Village, Greenwood Village, Colorado, United States, 80111, Littleton, Colorado, United States, 80120, Littleton, Colorado, United States, 80122, Lone Tree, Colorado, United States, 80124, Wheat Ridge, Colorado, United States, 80033, Hartford, Connecticut, United States, 06102, Smilow Cancer Hospital Care Center at Saint Francis, Hartford, Connecticut, United States, 06105, New Britain, Connecticut, United States, 06050, New Haven, Connecticut, United States, 06520, Washington, District of Columbia, United States, 20016, Altamonte Springs, Florida, United States, 32701, UM Sylvester Comprehensive Cancer Center at Deerfield Beach, Deerfield Beach, Florida, United States, 33442, Fort Lauderdale, Florida, United States, 33308, Jackson Memorial Hospital-Holtz Children's Hospital, University of Miami Miller School of Medicine-Sylvester Cancer Center, AdventHealth Medical Group Urology at Orlando, Winter Park, Florida, United States, 32792, Emory University Hospital/Winship Cancer Institute, Northeast Georgia Medical Center-Gainesville, Gainesville, Georgia, United States, 30501, Memorial Health University Medical Center, Lewis Cancer and Research Pavilion at Saint Joseph's/Candler, Saint Alphonsus Cancer Care Center-Caldwell, Coeur d'Alene, Idaho, United States, 83814, Saint Luke's Cancer Institute - Fruitland, Kootenai Clinic Cancer Services - Post Falls, Saint Luke's Cancer Institute - Twin Falls, Bloomington, Illinois, United States, 61701, Bloomington, Illinois, United States, 61704, Carbondale, Illinois, United States, 62902, Carterville, Illinois, United States, 62918, Centralia, Illinois, United States, 62801, Cancer Care Specialists of Illinois - Decatur, Effingham, Illinois, United States, 62401, Galesburg, Illinois, United States, 61401, Northwestern Medicine Cancer Center Delnor, Sudarshan K Sharma MD Limited-Gynecologic Oncology, Mount Vernon, Illinois, United States, 62864, OSF Saint Francis Radiation Oncology at Pekin Cancer Treatment Center, OSF Saint Francis Radiation Oncology at Peoria Cancer Center, Princeton, Illinois, United States, 61356, Central Illinois Hematology Oncology Center, Springfield, Illinois, United States, 62702, Southern Illinois University School of Medicine, Springfield, Illinois, United States, 62781, Northwestern Medicine Cancer Center Warrenville, Warrenville, Illinois, United States, 60555, Yorkville, Illinois, United States, 60560, Evansville, Indiana, United States, 47713, Fort Wayne, Indiana, United States, 46804, Fort Wayne, Indiana, United States, 46805, Fort Wayne, Indiana, United States, 46845, Indiana University/Melvin and Bren Simon Cancer Center, Indianapolis, Indiana, United States, 46202, Saint Vincent Hospital and Health Care Center, Indianapolis, Indiana, United States, 46260, South Bend, Indiana, United States, 46601, Medical Oncology and Hematology Associates-West Des Moines, Medical Oncology and Hematology Associates-Des Moines, Medical Oncology and Hematology Associates-Laurel, McFarland Clinic PC-Trinity Cancer Center, University of Iowa/Holden Comprehensive Cancer Center, West Des Moines, Iowa, United States, 50266-7700, West Des Moines, Iowa, United States, 50266, Garden City, Kansas, United States, 67846, Kansas City, Kansas, United States, 66160, Crestview Hills, Kentucky, United States, 41017, Saint Joseph Radiation Oncology Resource Center, Lexington, Kentucky, United States, 40504, Lexington, Kentucky, United States, 40509, University of Kentucky/Markey Cancer Center, Lexington, Kentucky, United States, 40536, Louisville, Kentucky, United States, 40202, Louisville, Kentucky, United States, 40245, Pikeville, Kentucky, United States, 41501, Baton Rouge, Louisiana, United States, 70809, Baton Rouge, Louisiana, United States, 70817, Mary Bird Perkins Cancer Center - Covington, Covington, Louisiana, United States, 70433, Louisiana State University Health Science Center, New Orleans, Louisiana, United States, 70112, MaineHealth Coastal Cancer Treatment Center, MaineHealth Cancer Care Center of York County, Baltimore, Maryland, United States, 21204, Walter Reed National Military Medical Center, Bethesda, Maryland, United States, 20889-5600, Silver Spring, Maryland, United States, 20910, Springfield, Massachusetts, United States, 01199, Ann Arbor, Michigan, United States, 48106, Battle Creek, Michigan, United States, 49017, IHA Hematology Oncology Consultants-Brighton, IHA Hematology Oncology Consultants-Canton, IHA Hematology Oncology Consultants-Chelsea, Hematology Oncology Consultants-Clarkston, Clarkston, Michigan, United States, 48346, Wayne State University/Karmanos Cancer Institute, Great Lakes Cancer Management Specialists-Doctors Park, East China Township, Michigan, United States, 48054, Genesee Cancer and Blood Disease Treatment Center, Grand Blanc, Michigan, United States, 48439, Helen DeVos Children's Hospital at Spectrum Health, Grand Rapids, Michigan, United States, 49503, Grosse Pointe Woods, Michigan, United States, 48236, Great Lakes Cancer Management Specialists-Van Elslander Cancer Center, Michigan Breast Specialists-Grosse Pointe Woods, Kalamazoo, Michigan, United States, 49007, Kalamazoo, Michigan, United States, 49048, Great Lakes Cancer Management Specialists-Macomb Medical Campus, Michigan Breast Specialists-Macomb Township, Saint Mary's Oncology/Hematology Associates of Marlette, Cancer and Hematology Centers of Western Michigan - Norton Shores, Norton Shores, Michigan, United States, 49444, Port Huron, Michigan, United States, 48060, Reed City, Michigan, United States, 49677, Great Lakes Cancer Management Specialists-Rochester Hills, Rochester Hills, Michigan, United States, 48309, Oncology Hematology Associates of Saginaw Valley PC, Saint Joseph, Michigan, United States, 49085, Ascension Providence Hospitals - Southfield, Southfield, Michigan, United States, 48075, Sterling Heights, Michigan, United States, 48312, Tawas City, Michigan, United States, 48764, Traverse City, Michigan, United States, 49684, Great Lakes Cancer Management Specialists-Macomb Professional Building, Saint Mary's Oncology/Hematology Associates of West Branch, West Branch, Michigan, United States, 48661, Ypsilanti, Michigan, United States, 48106, IHA Hematology Oncology Consultants-Ann Arbor, Ypsilanti, Michigan, United States, 48197, Burnsville, Minnesota, United States, 55337, Coon Rapids, Minnesota, United States, 55433, Hutchinson, Minnesota, United States, 55350, Fairview Clinics and Surgery Center Maple Grove, Maple Grove, Minnesota, United States, 55369, Minnesota Oncology Hematology PA-Maplewood, Maplewood, Minnesota, United States, 55109, Minneapolis, Minnesota, United States, 55407, Minneapolis, Minnesota, United States, 55415, Minneapolis, Minnesota, United States, 55454, Monticello, Minnesota, United States, 55362, Robbinsdale, Minnesota, United States, 55422, Rochester, Minnesota, United States, 55905, Saint Louis Park, Minnesota, United States, 55416, Saint Paul, Minnesota, United States, 55101, Saint Paul, Minnesota, United States, 55102, Shakopee, Minnesota, United States, 55379, Stillwater, Minnesota, United States, 55082, Minnesota Oncology Hematology PA-Woodbury, Woodbury, Minnesota, United States, 55125, Jackson, Mississippi, United States, 39216, Pascagoula, Mississippi, United States, 39581, Bonne Terre, Missouri, United States, 63628, Cape Girardeau, Missouri, United States, 63703, Jefferson City, Missouri, United States, 65109, Saint Joseph, Missouri, United States, 64506, Saint Louis Cancer and Breast Institute-South City, Saint Louis, Missouri, United States, 63109, Saint Louis, Missouri, United States, 63128, Saint Louis, Missouri, United States, 63131, Saint Louis, Missouri, United States, 63141, Sainte Genevieve County Memorial Hospital, Sainte Genevieve, Missouri, United States, 63670, Springfield, Missouri, United States, 65804, Springfield, Missouri, United States, 65807, Missouri Baptist Outpatient Center-Sunset Hills, Sunset Hills, Missouri, United States, 63127, Saint James Community Hospital and Cancer Treatment Center, Benefis Healthcare- Sletten Cancer Institute, Great Falls, Montana, United States, 59405, Saint Patrick Hospital - Community Hospital, Grand Island, Nebraska, United States, 68803, Alegent Health Bergan Mercy Medical Center, Comprehensive Cancer Centers of Nevada - Henderson, Radiation Oncology Centers of Nevada Central, Radiation Oncology Centers of Nevada Southeast, Comprehensive Cancer Centers of Nevada - Northwest, Alliance for Childhood Diseases/Cure 4 the Kids Foundation, Comprehensive Cancer Centers of Nevada - Town Center, Comprehensive Cancer Centers of Nevada-Summerlin, Comprehensive Cancer Centers of Nevada - Central Valley, Lebanon, New Hampshire, United States, 03756, Basking Ridge, New Jersey, United States, 07920, Lakewood, New Jersey, United States, 08701, Long Branch, New Jersey, United States, 07740, Middletown, New Jersey, United States, 07748, Moorestown, New Jersey, United States, 08057, Mount Holly, New Jersey, United States, 08060, Mullica Hill, New Jersey, United States, 08062, Paramus, New Jersey, United States, 07652, Ridgewood, New Jersey, United States, 07450, Toms River, New Jersey, United States, 08755, Vineland, New Jersey, United States, 08360, Voorhees, New Jersey, United States, 08043, Westwood, New Jersey, United States, 07675, Lovelace Medical Center-Saint Joseph Square, Albuquerque, New Mexico, United States, 87102, Southwest Gynecologic Oncology Associates Inc, Albuquerque, New Mexico, United States, 87106, Albuquerque, New Mexico, United States, 87109, Las Cruces, New Mexico, United States, 88011, Presbyterian Rust Medical Center/Jorgensen Cancer Center, Rio Rancho, New Mexico, United States, 87124, Montefiore Medical Center-Einstein Campus, State University of New York Downstate Medical Center, New York-Presbyterian/Brooklyn Methodist Hospital, Rochester, New York, United States, 14620, Rochester, New York, United States, 14642, Sleepy Hollow, New York, United States, 10591, Stony Brook, New York, United States, 11794, Uniondale, New York, United States, 11553, Asheboro, North Carolina, United States, 27203, Cone Health Cancer Center at Alamance Regional, Burlington, North Carolina, United States, 27215, UNC Lineberger Comprehensive Cancer Center, Chapel Hill, North Carolina, United States, 27599, Carolinas Medical Center/Levine Cancer Institute, Charlotte, North Carolina, United States, 28203, Novant Health Presbyterian Medical Center, Charlotte, North Carolina, United States, 28204, Charlotte, North Carolina, United States, 28207, Charlotte, North Carolina, United States, 28262, Clinton, North Carolina, United States, 28328, Southeastern Medical Oncology Center-Clinton, Southeastern Medical Oncology Center-Goldsboro, Goldsboro, North Carolina, United States, 27534, Greensboro, North Carolina, United States, 27403, Novant Health Cancer Institute - Huntersville, Huntersville, North Carolina, United States, 28078, Southern Oncology Specialists-Huntersville, Jacksonville, North Carolina, United States, 28546, Southeastern Medical Oncology Center-Jacksonville, Matthews, North Carolina, United States, 28105, Novant Health Cancer Specialists-Matthews, Mebane, North Carolina, United States, 27302, Novant Health Cancer Institute - Mooresville, Mooresville, North Carolina, United States, 28117, Reidsville, North Carolina, United States, 27320, Bismarck, North Dakota, United States, 58501, Fargo, North Dakota, United States, 58122, University of Cincinnati Cancer Center-UC Medical Center, Cleveland Clinic Cancer Center/Fairview Hospital, Ohio State University Comprehensive Cancer Center, Columbus Oncology and Hematology Associates Inc, Dayton Physician LLC-Miami Valley Hospital North, Delaware Health Center-Grady Cancer Center, Atrium Medical Center-Middletown Regional Hospital, Franklin, Ohio, United States, 45005-1066, Mayfield Heights, Ohio, United States, 44124, UH Seidman Cancer Center at Lake Health Mentor Campus, ProMedica Toledo Hospital/Russell J Ebeid Children's Hospital, University of Cincinnati Cancer Center-West Chester, Wright-Patterson Air Force Base, Ohio, United States, 45433, Genesis Healthcare System Cancer Care Center, University of Oklahoma Health Sciences Center, Oklahoma City, Oklahoma, United States, 73104, Oklahoma City, Oklahoma, United States, 73120, Oklahoma Cancer Specialists and Research Institute-Tulsa, Saint Alphonsus Medical Center-Baker City, Providence Cancer Institute Clackamas Clinic, Providence Willamette Falls Medical Center, Oregon City, Oregon, United States, 97045, Legacy Good Samaritan Hospital and Medical Center, Abington, Pennsylvania, United States, 19001, Allentown, Pennsylvania, United States, 18103, Saint Luke's University Hospital-Bethlehem Campus, Bethlehem, Pennsylvania, United States, 18015, Bethlehem, Pennsylvania, United States, 18017, Danville, Pennsylvania, United States, 17822, East Stroudsburg, Pennsylvania, United States, 18301, Easton, Pennsylvania, United States, 18042, Ephrata, Pennsylvania, United States, 17522, Gettysburg, Pennsylvania, United States, 17325, Lebanon, Pennsylvania, United States, 17042, Lewisburg, Pennsylvania, United States, 17837, Lewistown, Pennsylvania, United States, 17044, Philadelphia, Pennsylvania, United States, 19102, University of Pennsylvania/Abramson Cancer Center, Philadelphia, Pennsylvania, United States, 19104, Philadelphia, Pennsylvania, United States, 19107, Philadelphia, Pennsylvania, United States, 19111, Philadelphia, Pennsylvania, United States, 19140, Pittsburgh, Pennsylvania, United States, 15224, Pottsville, Pennsylvania, United States, 17901, West Reading, Pennsylvania, United States, 19611, Geisinger Wyoming Valley/Henry Cancer Center, Wilkes-Barre, Pennsylvania, United States, 18711, Willow Grove, Pennsylvania, United States, 19090, Providence, Rhode Island, United States, 02905, Prisma Health Cancer Institute - Spartanburg, Boiling Springs, South Carolina, United States, 29316, Easley, South Carolina, United States, 29640, Greenville Health System Cancer Institute-Andrews, Greenville, South Carolina, United States, 29601, Prisma Health Cancer Institute - Butternut, Greenville, South Carolina, United States, 29605, Prisma Health Greenville Memorial Hospital, Greenville, South Carolina, United States, 29607, Prisma Health Cancer Institute - Eastside, Greenville, South Carolina, United States, 29615, Greer, South Carolina, United States, 29650, Seneca, South Carolina, United States, 29672, Rapid City, South Dakota, United States, 57701, Sioux Falls, South Dakota, United States, 57104, Sioux Falls, South Dakota, United States, 57105, Sioux Falls, South Dakota, United States, 57117-5134, Knoxville, Tennessee, United States, 37920, Dell Seton Medical Center at The University of Texas, UT Southwestern/Simmons Cancer Center-Dallas, Galveston, Texas, United States, 77555-0565, American Fork Hospital / Huntsman Intermountain Cancer Center, American Fork, Utah, United States, 84003, Dixie Medical Center Regional Cancer Center, Salt Lake City, Utah, United States, 84106, Huntsman Cancer Institute/University of Utah, Salt Lake City, Utah, United States, 84112, Salt Lake City, Utah, United States, 84143, Portsmouth, Virginia, United States, 23708-2197, Virginia Commonwealth University/Massey Cancer Center, Providence Regional Cancer System-Aberdeen, Aberdeen, Washington, United States, 98520, Anacortes, Washington, United States, 98221, Virginia Mason Bainbridge Island Medical Center, Bainbridge Island, Washington, United States, 98110, Bellevue, Washington, United States, 98004, Swedish Cancer Institute-Eastside Oncology Hematology, Bellevue, Washington, United States, 98005, Bellingham, Washington, United States, 98225, Bellingham, Washington, United States, 98226, Harrison HealthPartners Hematology and Oncology-Bremerton, Bremerton, Washington, United States, 98310, Providence Regional Cancer System-Centralia, Centralia, Washington, United States, 98531, Edmonds, Washington, United States, 98026, Everett, Washington, United States, 98201, Virginia Mason Federal Way Medical Center, Federal Way, Washington, United States, 98002, Tacoma/Valley Radiation Oncology Centers-Gig Harbor, Gig Harbor, Washington, United States, 98332, Gig Harbor, Washington, United States, 98335, Issaquah, Washington, United States, 98029, Kennewick, Washington, United States, 99336, Kirkland, Washington, United States, 98033, Seattle Cancer Care Alliance at EvergreenHealth, Kirkland, Washington, United States, 98034, Longview, Washington, United States, 98632, Lynnwood, Washington, United States, 98036, Skagit Valley Hospital Regional Cancer Care Center, Mount Vernon, Washington, United States, 98274, Port Angeles, Washington, United States, 98362, Port Townsend, Washington, United States, 98368, Harrison HealthPartners Hematology and Oncology-Poulsbo, Poulsbo, Washington, United States, 98370, Puyallup, Washington, United States, 98372, Tacoma/Valley Radiation Oncology Centers-Puyallup, Seattle, Washington, United States, 98101, Seattle, Washington, United States, 98104, Seattle, Washington, United States, 98107, Seattle, Washington, United States, 98109, Seattle, Washington, United States, 98112, Seattle, Washington, United States, 98122-4307, Seattle, Washington, United States, 98122-5711, University of Washington Medical Center - Northwest, Seattle, Washington, United States, 98133, University of Washington Medical Center - Montlake, Seattle, Washington, United States, 98195, Providence Regional Cancer System-Shelton, Shelton, Washington, United States, 98584, MultiCare Deaconess Cancer and Blood Specialty Center - Valley, Spokane Valley, Washington, United States, 99216, Spokane, Washington, United States, 99202, MultiCare Deaconess Cancer and Blood Specialty Center - Downtown, Spokane, Washington, United States, 99204, Spokane, Washington, United States, 99216, Spokane, Washington, United States, 99218, MultiCare Deaconess Cancer and Blood Specialty Center - North, Tacoma/Valley Radiation Oncology Centers-Jackson Hall, Mary Bridge Children's Hospital and Health Center, Tacoma/Valley Radiation Oncology Centers-Saint Joe's, Vancouver, Washington, United States, 98664, Vancouver, Washington, United States, 98686, Providence Saint Mary Regional Cancer Center, Walla Walla, Washington, United States, 99362, Wenatchee, Washington, United States, 98801, North Star Lodge Cancer Center at Yakima Valley Memorial Hospital, Wheeling Hospital/Schiffler Cancer Center, Wheeling, West Virginia, United States, 26003, Fond Du Lac, Wisconsin, United States, 54937, Saint Vincent Hospital Cancer Center Green Bay, Green Bay, Wisconsin, United States, 54301, Green Bay, Wisconsin, United States, 54311, La Crosse, Wisconsin, United States, 54601, University of Wisconsin Hospital and Clinics, Marinette, Wisconsin, United States, 54143, Milwaukee, Wisconsin, United States, 53215, Milwaukee, Wisconsin, United States, 53226, Milwaukee, Wisconsin, United States, 53233, New Richmond, Wisconsin, United States, 54017, Sheboygan, Wisconsin, United States, 53081, Two Rivers, Wisconsin, United States, 54241, West Allis, Wisconsin, United States, 53227, Kagoshima City, Kagoshima, Japan, 890-8760, Niigata University Medical and Dental Hospital, Keimyung University-Dongsan Medical Center, Dalseo-gu, Daegu, Korea, Republic of, 42601, Goyang-si, Gyeonggi-do, Korea, Republic of, 410-769, Jung-gu, Incheon, Korea, Republic of, 400-711, Seoul, Korea, Korea, Republic of, 135-710, Catholic University of Korea-Seoul Saint Mary's Hospital, Seoul, Korea, Korea, Republic of, 137-040, Seoul National University Bundang Hospital, Seongnam City, Kyeonggi-do, Korea, Republic of, 463-707, Yonsei University Health System-Severance Hospital, Kyung Hee University Hospital at Gangdong, Radiation, Intensity-Modulated Radiotherapy, Recurrence-free survival (RFS) [TimeFrame:From protocol registration to date of first documented recurrence, death or date of last contact, assessed up to 11 years], Overall survival (OS) [TimeFrame:From entry into the study to death; or for living patients, the date of last contact regardless of whether or not this contact is on a subsequent protocol, assessed up to 11 years], Local control [TimeFrame:Up to 11 years], Site(s) of recurrence [TimeFrame:Up to 11 years], Incidence of adverse events [TimeFrame:Up to 5 years], Patient risk-benefit [TimeFrame:Up to 11 years], Treatment compliance [TimeFrame:Up to 11 years], Quality of life [TimeFrame:Up to 9 months following the first day of treatment], Pathologically proven primary cervical cancer I-IIA with squamous cell carcinoma, adenosquamous carcinoma or adenocarcinoma initially treated with a standard radical hysterectomy with pelvic lymphadenectomy, Middle third penetration, clinical tumor >= 2 cm, Superficial third penetration, clinical tumor >= 5 cm, Middle or deep third penetration, clinical tumor >= 4 cm, Absolute neutrophil count (ANC) >= 1,500/mcl, Creatinine =< upper limit of normal (ULN) or calculated creatinine clearance >= 60 mL/min, Serum glutamic oxaloacetic transaminase (SGOT) =< 3 x normal, Gynecologic Oncology Group (GOG) performance status 0, 1, 2, Patients should not be randomized less than 3 weeks post-surgery but will not be acceptable for randomization more than 8 weeks post-surgery, Patients who have met the pre-entry requirements, Patients must have signed an approved informed consent and authorization permitting release of personal health information, Patients with tumor in the parametria, pelvic lymph nodes or any other extra uterine site or with positive surgical margins, Patients with septicemia or severe infection, Patients with intestinal obstruction or gastrointestinal bleeding, Patients with cervix cancer who have received any previous radiation or chemotherapy, Patients whose circumstances do not permit completion of the study or the required follow-up, Patients with renal abnormalities requiring modification of radiation field (pelvic kidney, renal transplant, etc. Most advanced and compassionate Cancer care available in your current region malignancy allowed. 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